The Most Advanced Technology for Lyme Detection Using C6*

Lyme disease detection via Accuplex™ includes screening for antibodies to C6, a method indicated by the 2018 ACVIM consensus update on Lyme borreliosis in dogs and cats.¹ This peptide is only expressed following natural infection or exposure, so a positive C6 result will not be reported from cross-reactivity with vaccinal antibodies.

While a positive Lyme C6 result indicates natural infection or exposure to Borrelia burgdorferi, the majority of dogs returning a positive result for any serological test will not develop clinical signs. To aid in the management of these cases, the downloadable Antech Lyme Algorithm can guide you through a thorough diagnostic workup, including an investigation into the presence or absence of proteinuria (as recommended by the ACVIM guidelines).

* Detects patient antibodies against the C6 peptide derived from the VlsE protein of Borrelia burgdorferi, the causative agent of Lyme disease. Like all C6 tests, a positive result indicates infection (past or present.) Most infected dogs show no or mild clinical signs, and do not develop the clinical syndrome of Lyme disease.

¹ Littman MP, Gerber B, Goldstein RE, Labato MA, Lappin MR, Moore GE. ACVIM consensus update on Lyme borreliosis in dogs and cats. J Vet Intern Med. 2018;32(3):887-903. https://doi.org/10.1111/jvim.15085