Pasteurellosis
Pasteurella multocida is commonly found in the upper respiratory tract of rabbits and has
been reported to cause clinical disease involving many organs. The classical presentation is an initial
serous, and later, a white to yellow mucopurulent, nasal discharge and sneezing. Other signs are usually
related to abscess formation in a wide range to tissues including dental roots, bone, skin, and other
organs. These signs are not pathognomonic for pasteurellosis, however, as other bacteria may cause similar
signs with respiratory disease and abscesses.
There are no consistent changes on routine blood testing. A positive culture is diagnostic, but false
negatives limit the sensitivity and therefore the usefulness of cultures. A positive or rising titer and a
positive PCR test from a nasopharyngeal swab confirms P. multocida as the causative agent, whereas
a negative result on both serology and PCR indicates that P. multocida is not involved. Nasal swabs
are less sensitive than nasopharyngeal swabs for PCR testing.
Regardless of the type of diagnostic testing being performed, proper sample collection and handling are
paramount for accurate test results. Refer to the table below for guidance in collecting the appropriate
specimen. Further questions can be directed toward our specially trained Avian and Exotics Customer Service
representatives or Veterinary Consultants.

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